Methodology
Fluorescence in situ hybridization (FISH)
Specimen Requirements
Formalin fixed, paraffin embedded (FFPE) tissue block or 3 unstained 4 µm thick sections on positively charged slides.
Storage and Transport
Room temperature
CPT Code
88366
Turnaround Time
5-7 Days
Methodology
Fluorescence in situ hybridization (FISH)
Specimen Requirements
Whole blood or bone marrow in green (sodium heparin) tube; 3 mL (minimum 1 mL).
Storage and Transport
Room temperature
CPT Codes
88271 x6; 88275 x6; 88291
Turnaround Time
3-5 Days
Methodology
Polymerase Chain Reaction (PCR)
Specimen Requirements
Formalin-fixed, paraffin-embedded (FFPE) tissues or 5-7 unstained slides, 7 µm thick sections.
Whole blood or bone marrow in EDTA (lavender); 3 mL (minimum 1 mL).
Storage and Transport
Room temperature
CPT Code
81261
81242
Turnaround Time
1-3 Days
Methodology
Real-time Polymerase Chain Reaction (PCR)
Specimen Requirements
Formalin-fixed, paraffin-embedded (FFPE) tissues or 5-7 unstained, 7 µm sections on regular slides. Decalcified tissue is not appropriate for PCR testing
Storage and Transport
Room temperature
CPT Code
81210
Turnaround Time
5-7 Days
Methodology Real-time Polymerase Chain Reaction (PCR)
Specimen Requirements
Formalin-fixed, paraffin-embedded (FFPE) tissues or 5-7 unstained, 7 µm sections on regular slides. Decalcified tissue is not appropriate for PCR testing
Storage and TransportRoom temperature
CPT Code
81235
Turnaround Time
5-7 Days
Methodology
Real-time Polymerase Chain Reaction (PCR)
Specimen Requirements
Whole blood or bone marrow in EDTA (lavender); 3 mL (minimum 1 mL).
Storage and Transport
Room temperature
CPT Code
81270
Turnaround Time
3-5 Days
Methodology
Real-time Polymerase Chain Reaction (PCR)
Specimen Requirements
Formalin-fixed, paraffin-embedded (FFPE) tissues or 5-7 unstained, 7 µm sections on regular slides.
Storage and Transport
Room temperature
CPT Codes
81275, 81276, 81311
Turnaround Time
5-7 Days
Methodology
Fluorescence in situ hybridization (FISH)
Specimen Requirements
Whole blood or bone marrow in green (sodium heparin) tube; 3 mL (minimum 1 mL) .
Storage and Transport
Room temperature
CPT Codes
88275 x5, 88271 x5, 88291
Turnaround Time
3-5 Days
Methodology
Polymerase Chain Reaction (PCR)
Specimen Requirements
Formalin-fixed, paraffin-embedded (FFPE) tissues for tumor AND normal epithelial tissue or blood sample.
or 5-7 unstained, 7 µm sections on regular slides.
Storage and Transport
Room temperature
CPT Code
81301
Turnaround Time
5-7 Days
Methodology
Fluorescence in situ hybridization (FISH)
Specimen Requirements
Formalin-fixed, paraffin-embedded (FFPE) tissues or 5-7 unstained, 7 µm sections on regular slides.
Storage and Transport
Room temperature
CPT Code
81275
Turnaround Time
5-7 Days
Methodology
Fluorescence in situ hybridization (FISH)
Specimen Requirements
Whole blood or bone marrow in green (sodium heparin) tube; 3 mL (minimum 1 mL).
Formalin-fixed, paraffin-embedded (FFPE) tissues or 5-7 unstained, 7 µm sections on regular slides.
Storage and Transport
Room temperature
CPT Code
Varies depending on the probes count
Turnaround Time
3-5 Days
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